Frequently Asked Provider Questions

Can ProteX be used for all assisted reproductive technology procedures: IUI, IVF, and ICSI?

Yes. If the procedure requires fresh collection of the male sample, ProteX may be used. This includes procedures where the sperm is utilized to fertilize an oocyte and then the embryo is frozen for future use.

Can ProteX be used to collect for the purposes of cryopreservation?

Yes. ProteX is an excellent choice for collections sent to cryobanks. Please note if a sample is collected in ProteX, processed, frozen, and then thawed, the sample may have different semen parameters than if it were simply collected fresh.

Can ProteX be used to collect samples historically found to be oligospermic (low concentration/sperm count)?

Yes. Since ProteX is the first and only collection method that protects sperm at the moment of collection, even male patients previously diagnosed as subfertile due to low count or low motility are very likely to see an improvement in their sample quality.

What kind of media should I use in ProteX?

ProteX may be used with any pH buffered media, commonly referred to as third generation sperm washing media. If your preferred media requires refrigeration, allow media to come to ambient room temperature prior to adding into ProteX. It is not recommended to use a yolk-based media with ProteX.

Can ProteX be used dry?

Yes. Our research shows that ProteX dry is superior to the specimen cup. Samples collected in a dry ProteX should be processed within 3-5 hours of collection. For maximum sample quality and long-term viability, the preferred method is to collect in ProteX using media.

Is incubation of the ProteX necessary prior to collection?

No. ProteX may remain at room temperature for best results.

Should ProteX samples be incubated or refrigerated after collection?

No, this is not necessary. ProteX samples should always be kept at room temperature and should not be artificially warmed or cooled before processing.

Are there published studies comparing ProteX to traditional collection methods?

Yes. There are many scientific studies published comparing semen parameters, biochemistry, temperature, and conception. Read the Published Abstracts or dive deeper into the data and read the Scientific Studies.

Does ProteX have MEA (mouse embryo assay) certification?

No. Instead, we perform a sperm survivability assay, and every lot comes with a certificate confirming biocompatibility. If sperm survive, and they are the first biological contact to the ProteX environment, then logically the embryo survives as well. If you are still interested in MEA testing, we do have the ability to culture embryos upon request.

Can patients purchase ProteX direct?

Yes, however there are specific requirements the patient must meet for us to process the order. As an alternative, providers may order ProteX for their patients and distribute directly from their clinic.

Is ProteX covered by insurance?

This varies by state. ProteX is considered one part of an infertility treatment, such as IVF. 15 states have laws that require insurance companies to cover infertility treatment 100%: Arkansas, Connecticut, Delaware, Hawaii, Illinois, Louisiana, Maryland, Massachusetts, Montana, New Hampshire, New Jersey, New York, Ohio, Rhode Island, West Virginia. Two states have laws that require insurance companies to offer coverage for infertility treatment: California, Texas.

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